Back | Abnormal Embryos |
All the HDBR embryos are genotyped at collection. The majority of the samples reflect the 46XX or 46 XY karyotype, however a small percentage are found to be karyotypically abnormal.
The movies below show volume renders of OPT models of karyotypically abnormal embryos. No staining has been used on the specimens, the images were captured using autofluorescence with a FITC filter. |
Triploidy |
Sample 676 CS13 - Karyotype 69, XXY | Sample 1235 CS16 - Karyotype 69, XXX | Sample 675 CS17 - Karyotype 69, XXX | ||
This embryo has a marked neural tube defect. |
Down's Syndrome |
Sample 729 CS11 - Karyotype 47, XX+21 | Sample 221 CS17 - Karyotype 47, XY +21 |
This embryo has a very immature heart. |
Turner's Syndrome |
Sample 938 CS14 - Karyotype 45X | Sample 904 CS16 - Karyotype 45X |
Normal karyotype with neural tube defect |
Sample 354 CS13 - Karyotype 46, XX | Sample 274 CS13 - Karyotype 46, XY | Sample 205 CS19 - Karyotype 46, XX | ||
Other models of embryos with abnormal karyotypes:
Karyotype |
Syndrome |
Stages available |
---|---|---|
45, X | Turners | CS12, CS14 (shown above), CS16 (shown above), CS19, CS22, 11PCW |
47, XX +21 or 47, XY +21 | Downs | CS11(shown above), CS12, CS16, CS17 (shown above), CS18 |
47, XXY | Kleinfelters | CS19 |
47, XX +13 | Patau | Stage unknown - Growth distortion |
47, XX +14 | Trisomy 14 | CS12 |
47, XY +15 / 46,XY | Trisomy 15 | Stage unknown - Growth distortion |
47, XX +16 or 47, XY +16 | Trisomy 16 | Stages unknown - Growth distortion |
47, XX +18 | Edwards | CS17 |
47, XX +22 | Trisomy 22 | CS10 |
48, XY +5 +8/ 46 XY | CS12 | |
69, XXY | Triploidy | CS13, CS16, CS17 (all shown above), CS22, CS23 |
46, XY or 46, XX | Normal karyotype with neural tube defect | CS13 (shown above), CS15, CS17, CS18, CS19 (shown above) |
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