• Volume render movies
  • Painted anatomical regions
  • Carnegie Stage Definition

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Carnegie Stage 23

The movie below shows a micro-CT scan of a CS23 embryo. Sample staining and micro-CT was performed by Newcastle Preclinical In Vivo Imaging (PIVI) facility. 3D data-sets were acquired using Skyscan 1176, Bruker-microCT.

 
14685, male.
 

 

The movies below show volume renders of OPT models. No staining has been used on any of the specimens and the images were captured using autofluorescence with a FITC filter.

 

 
N336 46XY
  
N448 46XY

 

 

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Carnegie Stage 23

The movie below shows anatomical domains defined in the N448 model. The domains have been manually defined in the OPT model using specialised software and then visualised using commercial rendering packages.

The various domains are: neural tube - orange; eye - dark blue; otic vesicle - yellow; dorsal root ganglia - cyan.

 

 
N462 46XX

 

 

 

 

 

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Carnegie Stage 23 Definition
A 3D model of the head of a human embryo, Carnegie stage 23

 

Age is approximately 56 postovulatory days

Length is approximately 23 - 32mm

The eyelids are starting to fuse at margins. The superficial vascular plexus is rapidly approaching the vertex of the head. The limbs have increased markedly in length and show more advanced differentiation of their subdivisions.

O'Rahilly R and Muller F [1987] Developmental Stages in Human Embryos. Carnegie Institute, Washington, Publication no. 637, and O'Rahilly R, Müller F (2010) Developmental stages in human embryos: revised and new measurements. Cells Tissues Organs. 192:73-84. PMID: 20185898.