Interactive CS12 Embryo Model


        Key to anatomical regions

  • Neural tube
  • Optic vesicle
  • Otic vesicle
  • Somites/dermatomes
  • Heart
  • Liver

Movies of CS12 embryos


The movies below show volume renders of OPT models. No staining has been used on any of the specimens and the images were captured using autofluorescence with a FITC filter.


CS12 N288 46XX
CS12 N476 46XX



Painted Anatomical Regions


The movies below show anatomical domains defined in the N288 and N476 models. The domains have been manually defined in the OPT models using specialised software and then visualised using commercial rendering packages.

The various domains are: neural tube - orange; heart - red; liver - dark green; optic vesicle - dark blue; otic vesicle - yellow; dermatomes - cyan.


N288 46XX
N476 46XX

Carnegie Stage 12 Definition

a 3D model of a human embryo, Carnegie stage 12



Age is approximately 30 postovulatory days

Length is approximately 3 - 5 mm

External Features Include: a characteristic curved posture, three pharyngeal arches are visible, the caudal neuropore is closing or closed; the otic vesicles are almost closed but not detached; the upper limb buds are beginning to appear.

O'Rahilly R and Muller F [1987] Developmental Stages in Human Embryos. Carnegie Institute, Washington, Publication no. 637, and O'Rahilly R, Müller F (2010) Developmental stages in human embryos: revised and new measurements. Cells Tissues Organs. 192:73-84. PMID: 20185898.