Carnegie Stage 12 |
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Key to anatomical regions
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Movies of CS12 embryos |
The movies below show volume renders of OPT models. No staining has been used on any of the specimens and the images were captured using autofluorescence with a FITC filter.
| CS12 N288 46XX |
CS12 N476 46XX |
Painted Anatomical Regions |
The movies below show anatomical domains defined in the N288 and N476 models. The domains have been manually defined in the OPT models using specialised software and then visualised using commercial rendering packages.
The various domains are: neural tube - orange; heart - red; liver - dark green; optic vesicle - dark blue; otic vesicle - yellow; dermatomes - cyan.
| N288 46XX |
N476 46XX |
Carnegie Stage 12 Definition |
Age is approximately 30 postovulatory days
Length is approximately 3 - 5 mm
External Features Include: a characteristic curved posture, three pharyngeal arches are visible, the caudal neuropore is closing or closed; the otic vesicles are almost closed but not detached; the upper limb buds are beginning to appear.
O'Rahilly R and Muller F [1987] Developmental Stages in Human Embryos. Carnegie Institute, Washington, Publication no. 637, and O'Rahilly R, Müller F (2010) Developmental stages in human embryos: revised and new measurements. Cells Tissues Organs. 192:73-84. PMID: 20185898.
Other CS12 Resources
