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Interactive CS23 Embryo Model

 

The model is high resolution. Please allow time for it to load.

        Key to anatomical regions

  • Central nervous system
  • Eye
  • Ear
  • Dorsal root ganglia
  • Heart
  • Liver
  • Trachea and lungs
  • Gastrointestinal tract
  • Adrenal
  • Kidney
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Movies of CS23 embryos

 

The movie below shows a micro-CT scan of a CS23 embryo. Sample staining and micro-CT was performed by Newcastle
Preclinical In Vivo Imaging (PIVI) facility. 3D data-sets were acquired using Skyscan 1176, Bruker-microCT.

 
14685, male.
 

 

The movies below show volume renders of OPT models.
Images of autofluorescence from unstained samples were captured using a FITC filter.

 
N336 46XY
 
N448 46XY

 

 

 

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Painted Anatomical Regions

 

The movies below show anatomical domains defined in CS23 models.
The domains have been manually defined using specialised software and then visualised using commercial rendering packages.

 

14685 domains: neural tube - orange; eye - dark blue; otic vesicle - yellow; dorsal root ganglia - light blue; heart - red; liver - dark green;
gastrointestinal tract - cyan; lungs and trachea - lilac; adrenal - dark grey; kidney - pale pink.

 
14685, male

 

N448 domains: neural tube - orange; eye - dark blue; otic vesicle - yellow; dorsal root ganglia - cyan.

N448 46XY

 

 

 

 

 

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Carnegie Stage 23 Definition

 

 

A 3D model of a human embryo, Carnegie stage 21

 

Age is approximately 56 postovulatory days

Length is approximately 23 - 32mm

The eyelids are starting to fuse at margins. The superficial vascular plexus is rapidly approaching the vertex of the head. The limbs have increased markedly in length and show more advanced differentiation of their subdivisions.

O'Rahilly R and Muller F [1987] Developmental Stages in Human Embryos. Carnegie Institute, Washington, Publication no. 637, and O'Rahilly R, Müller F (2010) Developmental stages in human embryos: revised and new measurements. Cells Tissues Organs. 192:73-84. PMID: 20185898.