HDBR Publications

Authors Year Title Journal Link
S. M. McGlacken-Byrne et. al. 2022 Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency JCI Insight https://doi.org/10.1172/jci.insight.154671
D. J. Henderson et. al. 2022 Development of the Human Arterial Valves: Understanding Bicuspid Aortic Valve Frontiers in Cardiovascular Medicine https://doi.org/10.3389/fcvm.2021.802930
R. Al-Jawahiri et. al. 2022 SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile Genetics in Medicine  https://doi.org/10.1016/j.gim.2022.02.013
A Bhaduri et. al. 2021 An atlas of cortical arealization identifies dynamic molecular signatures Nature https://doi.org/10.1038/s41586-021-03910-8
P. Haldipur et. al. 2021 Evidence of disrupted rhombic lip development in the pathogenesis of Dandy–Walker malformation Acta Neuropathologica https://doi.org/10.1007/s00401-021-02355-7 
D. Fawkner-Corbett et. al. 2021 Spatiotemporal analysis of human intestinal development at single-cell resolution Cell https://doi.org/10.1016/j.cell.2020.12.016
R. H. Anderson et. al. 2021 The morphogenesis of abnormal coronary arteries in the congenitally malformed heart J Thorac Cardiovasc Surg https://doi.org/10.1016/j.jtcvs.2021.08.084
J. Collin et. al. 2021 Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface Ocul Surf https://doi.org/10.1016/j.jtos.2020.05.013
A. M. Ranzoni et. al. 2021 Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis Cell Stem Cell https://doi.org/10.1016/j.stem.2020.11.015
I. Bantounas et. al. 2021 The miR-199a/214 Cluster Controls Nephrogenesis and Vascularization in a Human Embryonic Stem Cell Model Stem Cell Reports https://doi.org/10.1016/j.stemcr.2020.11.007
K. E. MacDuffie et. al. 2021 Rescuing human fetal tissue research in the United States: A call for additional regulatory reform Stem Cell Reports https://doi.org/10.1016/j.stemcr.2021.10.016
L. Godfrey et. al. 2021 H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells Leukemia https://doi.org/10.1038/s41375-020-0808-y
I. S. Muskens et. al. 2021 The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis Nature Communications https://doi.org/10.1038/s41467-021-21064-z
A. Gualtieri et. al. 2021 Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans Nature Communications https://doi.org/10.1038/s41467-021-21712-4
M. D. Young et. al. 2021 Single cell derived mRNA signals across human kidney tumors Nature Communications https://doi.org/10.1038/s41467-021-23949-5
G. G. Giobbe et. al. 2021 SARS-CoV-2 infection and replication in human gastric organoids Nature Communications https://doi.org/10.1038/s41467-021-26762-2
S. Rice et. al. 2021 A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program Nature Communications https://doi.org/10.1038/s41467-021-27270-z
M. Spencer Chapman et. al. 2021 Lineage tracing of human development through somatic mutations Nature https://doi.org/10.1038/s41586-021-03548-6
M. Haniffa et. al. 2021 A roadmap for the Human Developmental Cell Atlas Nature https://doi.org/10.1038/s41586-021-03620-1
R. Elmentaite et. al. 2021 Cells of the human intestinal tract mapped across space and time Nature https://doi.org/10.1038/s41586-021-03852-1
L. Jardine et. al. 2021 Blood and immune development in human fetal bone marrow and Down syndrome Nature https://doi.org/10.1038/s41586-021-03929-x
M. Shibataet. al. 2021 Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis Nature https://doi.org/10.1038/s41586-021-03952-y
M. Shibata et. al. 2021 Regulation of prefrontal patterning and connectivity by retinoic acid Nature https://doi.org/10.1038/s41586-021-03953-x
R. C. V. Tyser et. al. 2021 Single-cell transcriptomic characterization of a gastrulating human embryo Nature https://doi.org/10.1038/s41586-021-04158-y
S. Jansky et. al. 2021 Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma Nature Genetics https://doi.org/10.1038/s41588-021-00806-1
K. A. Aldinger et. al. 2021 Spatial and cell type transcriptional landscape of human cerebellar development Nature Neuroscience https://doi.org/10.1038/s41593-021-00872-y
E. Louka et. al. 2021 Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia J Exp Med https://doi.org/10.1084/jem.20180853
I. Žunić Išasegi et. al. 2021 Transient Subplate Sublayer Forms Unique Corridor for Differential Ingrowth of Associative Pulvinar and Primary Visual Projection in the Prospective Visual Cortical Areas of the Human Fetal Occipital Lobe Cerebral Cortex https://doi.org/10.1093/cercor/bhab197
D. Sun et. al. 2021 A functional genetic toolbox for human tissue-derived organoids bioRxiv https://doi.org/10.1101/2020.05.04.076067
F. McLeod et. al. 2021 Altered synaptic connectivity in an in vitro human model of STXBP1 encephalopathy bioRxiv https://doi.org/10.1101/2021.09.22.461333
J. R. Harman et. al. 2021 A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes Genome Res https://doi.org/10.1101/gr.268490.120
G. Reynolds et. al. 2021 Developmental cell programs are co-opted in inflammatory skin disease Science https://doi.org/10.1126/science.aba6500
I. Drissi et. al. 2021 Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly J Med Genet https://doi.org/10.1136/jmedgenet-2020-107237
J. R. Tejedor et. al. 2021 Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia The Journal of Clinical Investigation https://doi.org/10.1172/JCI138833
S. M. McGlacken-Byrne et. al. 2021 ZSWIM7 Is Associated With Human Female Meiosis and Familial Primary Ovarian Insufficiency The Journal of Clinical Endocrinology & Metabolism https://doi.org/10.1210/clinem/dgab597
T. Rayon et. al. 2021 Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features Development https://doi.org/10.1242/dev.199711
L. C. Gregory et. al. 2021 The phenotypic spectrum associated with OTX2 mutations in humans Eur J Endocrinol https://doi.org/10.1530/eje-20-1453
T. R. Jackson et. al. 2021 The Origin of B-cells: Human Fetal B Cell Development and Implications for the Pathogenesis of Childhood Acute Lymphoblastic Leukemia Front Immunol https://doi.org/10.3389/fimmu.2021.637975
M. Rincic et. al. 2021 7p21.3 Together With a 12p13.32 Deletion in a Patient With Microcephaly-Does 12p13.32 Locus Possibly Comprises a Candidate Gene Region for Microcephaly? Front Mol Neurosci https://doi.org/10.3389/fnmol.2021.613091
S. L. Lindsay and S. C. Barnett 2021 Therapeutic Potential of Niche-Specific Mesenchymal Stromal Cells for Spinal Cord Injury Repair Cells https://doi.org/10.3390/cells10040901
L. Johnson Chacko et. al. 2021 Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs International Journal of Molecular Sciences https://doi.org/10.3390/ijms221910849
M. W. Mather et. al. 2021 Development of a physiological model of human middle ear epithelium Laryngoscope Investigative Otolaryngology https://doi.org/10.1002/lio2.661
D. Eigel et. al. 2021 Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures Biomaterials https://doi.org/10.1016/j.biomaterials.2021.120712
J. Collin et. al. 2021 A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells The Ocular Surface   https://doi.org/10.1016/j.jtos.2021.03.010
L. S. Hall et. al. 2020 Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders Molecular Psychiatry https://doi.org/10.1038/s41380-020-0743-3
A. B. Palmos et. al. 2020 Telomere length and human hippocampal neurogenesis Neuropsychopharmacology https://doi.org/10.1038/s41386-020-00863-w
S. Campinoti et. al. 2020 Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds Nature Communications https://doi.org/10.1038/s41467-020-20082-7
S. L. Lindsay et. al. 2020 Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates Nat Rev Neurol https://doi.org/10.1038/s41582-020-0311-0
A. Bhaduri et. al. 2020 Cell stress in cortical organoids impairs molecular subtype specification Nature https://doi.org/10.1038/s41586-020-1962-0
B. B. Cummings et. al. 2020 Transcript expression-aware annotation improves rare variant interpretation Nature https://doi.org/10.1038/s41586-020-2329-2
W. Sungnak et. al. 2020 SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes Nature Medicine https://doi.org/10.1038/s41591-020-0868-6
C. Muus et. al.r 2020 Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells bioRxiv https://doi.org/10.1101/2020.04.19.049254
J. R. Harman et. al. 2020 Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance bioRxiv https://doi.org/10.1101/2020.06.30.179796
P. A. Patkee et. al. 2020 Neurometabolite Mapping Highlights Elevated Myo-inositol Profiles within the Developing Brain in Down Syndrome bioRxiv https://doi.org/10.1101/2020.07.20.211805
G. Reynolds et. al. 2020 Poised cell circuits in human skin are activated in disease bioRxiv https://doi.org/10.1101/2020.11.05.369363
S. Rice et. al. 2020 A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL bioRxiv https://doi.org/10.1101/2020.11.15.379990
J.-E. Park et. al. 2020 A cell atlas of human thymic development defines T cell repertoire formation Science https://doi.org/10.1126/science.aay3224
T. Rayon et. al. 2020 Species-specific pace of development is associated with differences in protein stability Science https://doi.org/10.1126/science.aba7667
M. Heide et. al. 2020 Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset Science https://doi.org/10.1126/science.abb2401
E. M. Feneck et. al. 2020 Identification of a Primary Stroma and Novel Endothelial Cell Projections in the Developing Human Cornea Investigative ophthalmology & visual science https://doi.org/10.1167/iovs.61.6.5
P. Hua et. al. 2020 The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes Blood https://doi.org/10.1182/blood.2020005357
A. Roy 2020 A "gut feeling" about precursor B-ALL Blood https://doi.org/10.1182/blood.2020008907
P. Winer et. al. 2020 Germline variants in predisposition genes in children with Down syndrome and acute lymphoblastic leukemia Blood Advances https://doi.org/10.1182/bloodadvances.2019001216
M. D. Tharmalingam et. al. 2020 Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer BMC Med https://doi.org/10.1186/s12916-020-01844-y
M. Nakatomi et. al. 2020 Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development Development https://doi.org/10.1242/dev.189175
J. M. Fons et. al. 2020 Epithelial dynamics shed light on the mechanisms underlying ear canal defects Development https://doi.org/10.1242/dev.194654
L. A. Devlin et. al. 2020 Embryonic and foetal expression patterns of the ciliopathy gene CEP164 PLoS One https://doi.org/10.1371/journal.pone.0221914
J. M. Rieke et. al. 2020 SLC20A1 Is Involved in Urinary Tract and Urorectal Development Front Cell Dev Biol https://doi.org/10.3389/fcell.2020.00567
A. Alzu'bi et. al. 2020 Selective Expression of Nicotinic Receptor Sub-unit mRNA in Early Human Fetal Forebrain Front Mol Neurosci https://doi.org/10.3389/fnmol.2020.00072
T. Qiu et. al. 2020 Development of the Vestibular Lamina in Human Embryos: Morphogenesis and Vestibule Formation Front Physiol https://doi.org/10.3389/fphys.2020.00753
A. Güven et. al. 2020 Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex eLife https://doi.org/10.7554/eLife.49808
C. G. K. Ziegler et. al. 2020 SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues Cell   https://doi.org/10.1016/j.cell.2020.04.035
L. Xing et. al. 2020 Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex Neuron   https://doi.org/10.1016/j.neuron.2020.09.034
F. M. Lopes et. al. 2019 Overactivity or blockade of transforming growth factor-beta each generate a specific ureter malformation J Pathol https://doi.org/10.1002/path.5335 
C. B. Mellough et. al. 2019 Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences Stem Cells Transl Med https://doi.org/10.1002/sctm.18-0267 
R. J. Holt et. al. 2019 De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies Am J Hum Genet https://doi.org/10.1016/j.ajhg.2019.07.005
K. A. Aldinger et. al. 2019 Redefining the Etiologic Landscape of Cerebellar Malformations Am J Hum Genet https://doi.org/10.1016/j.ajhg.2019.07.019
S. Desiderio et. al. 2019 Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA Cell Rep https://doi.org/10.1016/j.celrep.2019.02.097
M. Kostic et. al. 2019 YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex Cell Rep https://doi.org/10.1016/j.celrep.2019.03.091
L. C. Gregory et. al. 2019 Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation EBioMedicine https://doi.org/10.1016/j.ebiom.2019.03.013
R. Alharatani et. al. 2019 Expression of the guanine nucleotide exchange factor, RAPGEF5, during mouse and human embryogenesis Gene Expr Patterns https://doi.org/10.1016/j.gep.2019.119057
N. Kalebic, et. al. 2019 Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology Cell Stem Cell https://doi.org/10.1016/j.stem.2019.02.017
J. M. Segal et. al. 2019 Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors Nat Commun https://doi.org/10.1038/s41467-019-11266-x
M. Cardoso-Moreira et. al. 2019 Gene expression across mammalian organ development Nature https://doi.org/10.1038/s41586-019-1338-5
I. Sarropoulos et. al. 2019 Developmental dynamics of lncRNAs across mammalian organs and species Nature https://doi.org/10.1038/s41586-019-1341-x
D.-M. Popescu et. al. 2019 Decoding human fetal liver haematopoiesis Nature https://doi.org/10.1038/s41586-019-1652-y
R. N. Doan et. al. 2019 Recessive gene disruptions in autism spectrum disorder Nat Genet https://doi.org/10.1038/s41588-019-0433-8
C. J. McCann et. al. 2019 Neuronal Development and Onset of Electrical Activity in the Human Enteric Nervous System Gastroenterology https://doi.org/10.1053/j.gastro.2018.12.020
J. M. Tilghman et. al. 2019 Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease N Engl J Med https://doi.org/10.1056/NEJMoa1706594
A. Alzu'bi, et. al. 2019 Thalamocortical Afferents Innervate the Cortical Subplate much Earlier in Development in Primate than in Rodent Cereb Cortex https://doi.org/10.1093/cercor/bhy327
C. H. Spurrell et. al. 2019 Genome-Wide Fetalization of Enhancer Architecture in Heart Disease bioRxiv https://doi.org/10.1101/591362
I. Kostovic et. al. 2019 Sublaminar organization of the human subplate: developmental changes in the distribution of neurons, glia, growing axons and extracellular matrix J Anat https://doi.org/10.1111/joa.12920
A. Alzu'bi and G. J. Clowry 2019 Expression of ventral telencephalon transcription factors ASCL1 and DLX2 in the early fetal human cerebral cortex J Anat https://doi.org/10.1111/joa.12971
B. J. Stewart et. al. 2019 Spatiotemporal immune zonation of the human kidney Science https://doi.org/10.1126/science.aat5031
P. Haldipur et. al. 2019 Spatiotemporal expansion of primary progenitor zones in the developing human cerebellum Science https://doi.org/10.1126/science.aax7526
L. J. Ewans et. al. 2019 Pathogenic variants in PLOD3 result in a Stickler syndrome-like connective tissue disorder with vascular complications J Med Genet https://doi.org/10.1136/jmedgenet-2019-106019
A. C. Houweling et. al. 2019 Loss-of-function variants in myocardin cause congenital megabladder in humans and mice J Clin Invest https://doi.org/10.1172/jci128545
R. Seselgyte et. al. 2019 Disruption of FOXF2 as a Likely Cause of Absent Uvula in an Egyptian Family J Dent Res https://doi.org/10.1177/0022034519837245
T. H. N. Teshima et. al. 2019 Dual Sympathetic Input into Developing Salivary Glands J Dent Res https://doi.org/10.1177/0022034519865222
C. Bueno et. al. 2019 Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL Blood https://doi.org/10.1182/blood.2019000893
S. O'Byrne et. al. 2019 Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs Blood https://doi.org/10.1182/blood.2019001289
P. Hua et. al. 2019 Single-cell analysis of bone marrow–derived CD34+ cells from children with sickle cell disease and thalassemia Blood https://doi.org/10.1182/blood.2019002301
D. Sánchez-Martínez et. al. 2019 Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia Blood https://doi.org/10.1182/blood-2018-10-882944
C. Melau et. al. 2019 Characterization of Human Adrenal Steroidogenesis During Fetal Development J Clin Endocrinol Metab https://doi.org/10.1210/jc.2018-01759
L. C. Gregory et. al. 2019 Mutations in MAGEL2 and L1CAM are associated with congenital hypopituitarism and arthrogryposis J Clin Endocrinol Metab https://doi.org/10.1210/jc.2019-00631
C. B. Mellough et. al. 2019 An integrated transcriptional analysis of the developing human retina Development https://doi.org/10.1242/dev.169474
M. Ahmed et. al. 2019 Laminin alpha2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development Development https://doi.org/10.1242/dev.172668
P. J. O'Shaughnessy et. al. 2019 Alternative (backdoor) androgen production and masculinization in the human fetus PLoS Biol https://doi.org/10.1371/journal.pbio.3000002
H. Hardy et. al. 2019 Detailed analysis of chick optic fissure closure reveals Netrin-1 as an essential mediator of epithelial fusion eLife https://doi.org/10.7554/eLife.43877
C. M. Kolvenbach et. al. 2019 Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction The American Journal of Human Genetics https://doi.org/10.1016/j.ajhg.2019.03.023
S. Mayer et. al. 2019 Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex Neuron   https://doi.org/10.1016/j.neuron.2019.01.027
T. Namba et. al. 2019 Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis Neuron   https://doi.org/10.1016/j.neuron.2019.11.027
A. C. Thomas et. al. 2018 Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development Birth Defects Res https://doi.org/10.1002/bdr2.1183 
J. Liu et. al. 2018 Nestin-expressing cell types in the temporal lobe and hippocampus: Morphology, differentiation, and proliferative capacity Glia https://doi.org/10.1002/glia.23211 
F. Memi et. al. 2018 Multiple roles of Sonic Hedgehog in the developing human cortex are suggested by its widespread distribution Brain Struct Funct https://doi.org/10.1007/s00429-018-1621-5 
M. Felemban et. al. 2018 Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix Acta Biomater https://doi.org/10.1016/j.actbio.2018.05.023 
A. Wilderman et. al. 2018 High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development Cell Rep https://doi.org/10.1016/j.celrep.2018.03.129
A. Jorgensen et. al. 2018 Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis Cell Rep https://doi.org/10.1016/j.celrep.2018.10.064
C. Boiers et. al. 2018 A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1 Dev Cell https://doi.org/10.1016/j.devcel.2017.12.005
K. R. Long et. al. 2018 Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex Neuron https://doi.org/10.1016/j.neuron.2018.07.013
G. J. Clowry et. al. 2018 Charting the protomap of the human telencephalon Semin Cell Dev Biol https://doi.org/10.1016/j.semcdb.2017.08.033
M. Z. Ozair et. al. 2018 hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate Cell Stem Cell https://doi.org/10.1016/j.stem.2018.05.024
B. Dorgau et. al. 2018 Laminin gamma3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation Cell Death Dis https://doi.org/10.1038/s41419-018-0648-0
M. T. Dell’Anno et. al. 2018 Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit Nature Communications https://doi.org/10.1038/s41467-018-05844-8
V. I. Floros et. al. 2018 Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos Nat Cell Biol https://doi.org/10.1038/s41556-017-0017-8
R. Vento-Tormo et. al. 2018 Single-cell reconstruction of the early maternal-fetal interface in humans Nature https://doi.org/10.1038/s41586-018-0698-6
C. G. F. de Kovel et. al. 2018 Subtle left-right asymmetry of gene expression profiles in embryonic and foetal human brains Sci Rep https://doi.org/10.1038/s41598-018-29496-2
C. G. F. de Kovel et. al. 2018 Transcriptomic analysis of left-right differences in human embryonic forebrain and midbrain Sci Data https://doi.org/10.1038/sdata.2018.164
M. F. Portnoi et. al. 2018 Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies Hum Mol Genet https://doi.org/10.1093/hmg/ddy037
J. MacDonald et. al. 2018 DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads Hum Reprod https://doi.org/10.1093/humrep/dey289
M. D. Young et. al. 2018 Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors Science https://doi.org/10.1126/science.aat1699
M. Li et. al. 2018 Integrative functional genomic analysis of human brain development and neuropsychiatric risks Science https://doi.org/10.1126/science.aat7615
H. E. O'Brien et. al. 2018 Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders Genome Biol https://doi.org/10.1186/s13059-018-1567-1
J. Y. W. Liu et. al. 2018 Doublecortin-expressing cell types in temporal lobe epilepsy Acta Neuropathol Commun https://doi.org/10.1186/s40478-018-0566-5
S. Behjati et. al. 2018 Mapping human development at single-cell resolution Development https://doi.org/10.1242/dev.152561
P. Hurtado-Gonzalez et. al. 2018 Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems Environ Health Perspect https://doi.org/10.1289/ehp2307
R. Wilson et. al. 2018 Human peptidergic nociceptive sensory neurons generated from human epidermal neural crest stem cells (hEPI-NCSC) PLoS One https://doi.org/10.1371/journal.pone.0199996
N. O. Lindstrom et. al. 2018 Conserved and Divergent Features of Human and Mouse Kidney Organogenesis J Am Soc Nephrol https://doi.org/10.1681/asn.2017080887
L. Eley et. al. 2018 A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice Elife https://doi.org/10.7554/eLife.34110
K. Oprych et. al. 2017 Common olfactory ensheathing glial markers in the developing human olfactory system Brain Struct Funct https://doi.org/10.1007/s00429-016-1313-y
A. Alzu'bi et. al. 2017 Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2 and COUP-TFII in early fetal human telencephalon Brain Struct Funct https://doi.org/10.1007/s00429-016-1343-5 
R. Holt et. al. 2017 Identification and functional characterisation of genetic variants in OLFM2 in children with developmental eye disorders Hum Genet https://doi.org/10.1007/s00439-016-1745-8 
C. G. de Kovel et. al. 2017 Left-Right Asymmetry of Maturation Rates in Human Embryonic Neural Development Biol Psychiatry https://doi.org/10.1016/j.biopsych.2017.01.016
J. Kerry et. al. 2017 MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia Cell Rep https://doi.org/10.1016/j.celrep.2016.12.054
A. Roy et. al. 2017 High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans Clin Immunol https://doi.org/10.1016/j.clim.2017.06.005
S. da Silva and C. L. Cepko 2017 Fgf8 Expression and Degradation of Retinoic Acid Are Required for Patterning a High-Acuity Area in the Retina Dev Cell https://doi.org/10.1016/j.devcel.2017.05.024
A. Gonzalez-Cordero et. al. 2017 Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors Stem Cell Reports https://doi.org/10.1016/j.stemcr.2017.07.022
G. Walko et. al. 2017 A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells Nature Communications https://doi.org/10.1038/ncomms14744
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