| Back | 3D Models of Human Embryos with Abnormal Karyotype |
All the HDBR embryos are genotyped at collection. The majority of the samples reflect the 46XX or 46 XY karyotype, however a small percentage are found to be karyotypically abnormal.
| The movies below show 3D models of karyotypically abnormal human embryos. |
Triploidy |
| Sample 676 CS13 - Karyotype 69, XXY | Sample 1235 CS16 - Karyotype 69, XXX | Sample 675 CS17 - Karyotype 69, XXX | ||
| This embryo has a marked neural tube defect. |
Down's Syndrome |
| Sample 729 CS11 - Karyotype 47, XX+21 | Sample 221 CS17 - Karyotype 47, XY +21 |
| This embryo has a very immature heart. |
Turner's Syndrome |
| Sample 938 CS14 - Karyotype 45X | Sample 904 CS16 - Karyotype 45X |
Normal karyotype with neural tube defect |
| Sample 354 CS13 - Karyotype 46, XX | Sample 274 CS13 - Karyotype 46, XY | Sample 205 CS19 - Karyotype 46, XX | ||
Other models of embryos with abnormal karyotypes are available:
Karyotype |
Syndrome |
Stages available |
|---|---|---|
| 45, X | Turners | CS12, CS14 (shown above), CS16 (shown above), CS19, CS22, 11PCW |
| 47, XX +21 or 47, XY +21 | Downs | CS11(shown above), CS12, CS16, CS17 (shown above), CS18 |
| 47, XXY | Kleinfelters | CS19 |
| 47, XX +13 | Patau | Stage unknown - Growth distortion |
| 47, XX +14 | Trisomy 14 | CS12 |
| 47, XY +15 / 46,XY | Trisomy 15 | Stage unknown - Growth distortion |
| 47, XX +16 or 47, XY +16 | Trisomy 16 | Stages unknown - Growth distortion |
| 47, XX +18 | Edwards | CS17 |
| 47, XX +22 | Trisomy 22 | CS10 |
| 48, XY +5 +8/ 46 XY | CS12 | |
| 69, XXY | Triploidy | CS13, CS16, CS17 (all shown above), CS22, CS23 |
| 46, XY or 46, XX | Normal karyotype with neural tube defect | CS13 (shown above), CS15, CS17, CS18, CS19 (shown above) |