Investigating the vertical transmission of SARS-CoV2

 

The gene expression data below has been kindly submitted by Dr Mattia Gerli at the UCL Great Ormond Street Institute of Child Health. The localisation of ACE2 (red) and TMPRSS2 (brown) has been studied in a variety of fetal tissues from 14PCW to 22PCW. Co-expression of these two proteins is known to be a prerequisite for SARS-CoV-2 infection. Please click here for the original publication.

 

Click on the images below to enlarge

 

 

Intestine

14PCW

18PCW

20PCW

22PCW

22PCW X40

 

 

Lung

 

 

Kidney

 

 

Bladder

 

 

Skin

 

 

Amniotic membrane

 

 

Placenta